Publications

Year

Project

Type

The modular serine proteases of the complement cascade.

Forneris F., Wu J., Gros P.

The modular serine proteases of the complement cascade.

Published in:  Current Opinions in Structural Biology, 22, 333-341 (2012). - DOI 10.1016/j.sbi.2012.04.001 - PMID 22560446

Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.

Hadders M.A., Bubeck D., Roversi P., Hakobyan S., Forneris F., Morgan B.P., Pangburn M.K., Llorca O., Lea S.M., Gros P.

Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.

Published in:  Cell Reports, 1, 200-207 (2012). - DOI 10.1016/j.celrep.2012.02.003 - PMID 22832194

Structures of C3b in complex with factors B and D give insight into complement convertase formation.

Forneris F., Ricklin D., Wu J., Tzekou A., Wallace R.S., Lambris J.D., Gros P.

Structures of C3b in complex with factors B and D give insight into complement convertase formation.

Published in:  Science, 330, 1816-1820 (2010). - DOI 10.1126/science.1195821 - PMID 21205667

Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2.

Binda C., Valente S., Romanenghi M., Pilotto S., Cirilli R., Karytinos A., Ciossani G., Botrugno O.A., Forneris F., Tardugno M., Edmondson D.E., Minucci S., Mattevi A., Mai A.

Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2.

Published in:  Journal of the American Chemical Society, 132, 6827-6833 (2010). - DOI 10.1021/ja101557k - PMID 20415477

Alternative splicing of the histone demethylase LSD1/KDM1 contributes to the modulation of neurite morphogenesis in the mammalian nervous system.

Zibetti C., Adamo A., Binda C., Forneris F., Toffolo E., Verpelli C., Ginelli E., Mattevi A., Sala C., Battaglioli E.

Alternative splicing of the histone demethylase LSD1/KDM1 contributes to the modulation of neurite morphogenesis in the mammalian nervous system.

Published in:  Journal of Neuroscience, 30, 2521-2532 (2010). - DOI 10.1523/JNEUROSCI.5500-09.2010 - PMID 20164337

Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization.

Villa F., Capasso P., Tortorici M., Forneris F., de Marco A., Mattevi A., Musacchio A.

Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization.

Published in:  Proceedings of the National Academy of Sciences, U.S.A., 106, 20204-20209 (2009). - DOI 10.1073/pnas.0908485106 - PMID 19918049

New roles of flavoproteins in molecular cell biology: histone demethylase LSD1 and chromatin.

Forneris F., Battaglioli E., Mattevi A., Binda C.

New roles of flavoproteins in molecular cell biology: histone demethylase LSD1 and chromatin.

Published in:  FEBS Journal, 276, 4304-4312 (2009). - DOI 10.1111/j.1742-4658.2009.07142.x - PMID 19624733

Multiple pathways guide oxygen diffusion into flavoenzyme active sites.

Baron R., Riley C., Chenprakhon P., Thotsaporn K., Winter R.T., Alfieri A., Forneris F., van Berkel W.J., Chaiyen P., Fraaije M.W., Mattevi A., McCammon J.A.

Multiple pathways guide oxygen diffusion into flavoenzyme active sites.

Published in:  Proceedings of the National Academy of Sciences, U.S.A., 106, 10603-10608 (2009). - DOI 10.1073/pnas.0903809106 - PMID 19541622

ThermoFAD, a Thermofluor-adapted flavin ad hoc detection system for protein folding and ligand binding.

Forneris F., Orru R., Bonivento D., Chiarelli L.R., Mattevi A.

ThermoFAD, a Thermofluor-adapted flavin ad hoc detection system for protein folding and ligand binding.

Published in:  FEBS Journal, 276, 2833-2840 (2009). - DOI 10.1111/j.1742-4658.2009.07006.x - PMID 19459938