Publications

Year

Project

Type

Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode

Forneris F., Wu J., Xue X., Ricklin D., Lin Z., Sfyroera G., Tzekou A., Volokhina E., Granneman J.C., Hauhart R., Bertram P., Liszewski M.K., Atkinson J.P., Lambris J.D., Gros P.

Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode

Published in:  The EMBO Journal, 35, 1133-1149 (2016). - DOI 10.15252/embj.201593673 - PMID 27013439

The three-dimensional Structure of Lonely Guy from Claviceps purpurea provides insights into the phosphoribohydrolase function of Rossmann fold-containing lysine decarboxylase-like proteins.

Dzurová L., Forneris F.*, Savino S., Galuszka P., Vrabka J., Frébort I.* (*Shared Corresponding Authors)

The three-dimensional Structure of Lonely Guy from Claviceps purpurea provides insights into the phosphoribohydrolase function of Rossmann fold-containing lysine decarboxylase-like proteins.

Published in:  Proteins, 83, 1539-1546 (2015). - DOI 10.1002/prot.24835 - PMID 26010010

Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation

Pilotto S., Speranzini V., Tortorici M., Durand D., Fish A., Valente S., Forneris F., Mai A., Sixma T.K., Vachette P., Mattevi A.

Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation

Published in:  Proceedings of the National Academy of Sciences, U.S.A., 112, 2752-2757 (2015). - DOI 10.1073/pnas.1419468112 - PMID 25730864

Ensemble refinement shows conformational flexibility in crystal structures of human complement factor D.

Forneris F., Burnley B.T., Gros P.

Ensemble refinement shows conformational flexibility in crystal structures of human complement factor D.

Published in:  Acta Crystallographica section D - Biological Crystallography, 70, 733-743 (2014). - DOI 10.1107/S1399004713032549 - PMID 24598742

Structures of Wnt-Antagonist ZNRF3 and Its Complex with R-Spondin 1 and Implications for Signaling.

Peng W.C., de Lau W., Madoori P.K., Forneris F., Granneman J.C., Clevers H., Gros P.

Structures of Wnt-Antagonist ZNRF3 and Its Complex with R-Spondin 1 and Implications for Signaling.

Published in:  PLoS One, 8, e83110 (2013). - DOI 10.1371/journal.pone.0083110 - PMID 24349440

Large extent of disorder in Adenomatous Polyposis Coli offers a strategy to guard Wnt signalling against point mutations.

Minde D.P., Radli M., Forneris F., Maurice M.M., Rüdiger S.G.

Large extent of disorder in Adenomatous Polyposis Coli offers a strategy to guard Wnt signalling against point mutations.

Published in:  PLoS One, 8, e77257 (2013). - DOI 10.1371/journal.pone.0077257 - PMID 24130866

Complement Factor D

Forneris F., Gros P.

Complement Factor D

Published in:  Handbook of Proteolytic Enzymes, 3, 2841-2848 (2013). - DOI 10.1016/B978-0-12-382219-2.00630-X

Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5.

Peng W.C., de Lau W., Forneris F., Granneman J.C., Huch M., Clevers H., Gros P.

Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5.

Published in:  Cell Reports, 3, 1885-1892 (2013). - DOI 10.1016/j.celrep.2013.06.009 - PMID 23809763

Proteolysis, Complex Formation and Conformational Changes Drive the Complement Pathways

Gros P., Forneris F.

Proteolysis, Complex Formation and Conformational Changes Drive the Complement Pathways

Published in:  Advancing Methods for Biomolecular Crystallography, 297-307 (2013). - DOI 10.1007/978-94-007-6232-9_25