Description
With guidance from previous structural studies and insights from clinical genetics, we carried out an extensive mutagenesis investigation to identify critical hot spots for the LH3 enzyme catalytic activity, and also gave the spark to new collaborations to study the structural features of LH enzymes using computational chemistry.

Project details
- Full title: Unraveling the Molecular Mechanisms of Collagen Glycosyltransferases
- Funding agency: Mizutani Foundation for Glycoscience
- Programme: Research Grant
- Project code: 200039
- Total project funding: EUR 27’087.00
- Project period: 1 April 2020 – 31 March 2022 (with granted extension)
- Institutions involved: University of Pavia (Italy)
Principal Investigator
Federico Forneris
Permanent Staff – Armenise-Harvard Laboratory
Former Lab Members Involved
Luigi Scietti
Lab Alumni – Armenise-Harvard Laboratory
Francesca De Giorgi
Lab Alumni – Armenise-Harvard Laboratory
Daiana Mattoteia
Lab Alumni – Armenise-Harvard Laboratory
Marco Fumagalli
Lab Alumni – Armenise-Harvard Laboratory
Matteo De Marco
Lab Alumni – Armenise-Harvard Laboratory





