Description
The project seeks a structural and enzymological understanding of human collagen prolyl 4-hydroxylase and uses that knowledge to enable drug-discovery research for fibrotic diseases and cancer.

Role of our laboratory
Structural and biophysical characterization of human collagen prolyl 4-hydroxylase I and II isoforms.
Project details
- Full title: Human collagen prolyl 4-hydroxylase: structural enzymological understanding and drug discovery research for fibrotic diseases and cancer
- Funding agency: Jane and Aatos Erkko Foundation
- Programme: Research Grant
- Project code: 2022
- Total project funding: EUR 724’000.00 (funding to the laboratory: EUR 60’000.00)
- Project period: 1 September 2022 – 31 August 2027 (with granted extension)
- Institutions involved: University of Oulu (Finland, Coordinator), University of Pavia
Partner Investigator
Federico Forneris
Permanent Staff – Armenise-Harvard Laboratory
Former Lab Members Involved
Matteo De Marco
Lab Alumni – Armenise-Harvard Laboratory

