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Jane and Aatos Erkko Foundation

Jane and Aatos Erkko Foundation, Research Grant: "Human collagen prolyl 4-hydroxylase: structural enzymological understanding and drug discovery research for fibrotic diseases and cancer" – Project code 2022

Description

The project seeks a structural and enzymological understanding of human collagen prolyl 4-hydroxylase and uses that knowledge to enable drug-discovery research for fibrotic diseases and cancer.

Jane and Aatos Erkko Foundation project image

Role of our laboratory

Structural and biophysical characterization of human collagen prolyl 4-hydroxylase I and II isoforms.

Project details

  • Full title: Human collagen prolyl 4-hydroxylase: structural enzymological understanding and drug discovery research for fibrotic diseases and cancer
  • Funding agency: Jane and Aatos Erkko Foundation
  • Programme: Research Grant
  • Project code: 2022
  • Total project funding: EUR 724’000.00 (funding to the laboratory: EUR 60’000.00)
  • Project period: 1 September 2022 – 31 August 2027 (with granted extension)
  • Institutions involved: University of Oulu (Finland, Coordinator), University of Pavia

Partner Investigator

Federico Forneris

Permanent Staff – Armenise-Harvard Laboratory

Former Lab Members Involved

Matteo De Marco

Lab Alumni – Armenise-Harvard Laboratory

Participants

Silvia Faravelli

Permanent Staff - Armenise-Harvard Laboratory

Michele Tiberi

Postdoctoral Fellows - Armenise-Harvard Laboratory

Research activities