Best wishes for a successful 2022 to everyone! Our team has experienced several challenges and is ready to tackle new scientific ones. We wish the best of luck to our senior postdoc Luigi Scietti, who obtained a tenured position as Head of Facility at the European Institute of Oncology (IEO) in Milan; to Tiziano Ongaro, joining Novartis in Basel; and to Serena Pantalone, who will soon defend her PhD thesis and will meanwhile start her new position in Pharma R&D. We welcome new PhD student Stefano Liberi, who was awarded a three-year PhD fellowship from IUSS, and new Master’s student Giorgia D’Angelo.