COVID-19
#covid19
Description
The SARS-CoV-2 pandemic has dramatically changed our lives and also our approach to doing research. In this respect, we actively engaged in several collaborations focusing on SARS-CoV-2 protein characterization, based on our expertise in protein production, biophysical analyses, and structural biology.
 |
Cartoon representation of the crystal structure of the complex between SARS-CoV-2 RBD and human ACE2 ectodomain. hACE2 is colored in wheat, SARS-CoV-2 RBD in magenta. Interface residues are shown with green and yellow sticks. |
Resources
PDB Files:
Publications and Dissemination
Publications
- Oliviero B., Kumar S., Conteianni D., Donetti G., Cerino A., Iraci A.S., La Gaipa A., Ottolini S., Tengattini S., Massolini G., Cassaniti I., Sammartino J.C., Mele D., Baldanti F., Forneris F., Faravelli S., Scotti C., Pessino G., Maggi M., Mantovani S., Temporini C., Mondelli M.U., Terreni M. Selection of Functional Glycoforms in Anti-SARS-CoV-2 Human Ig1 Monoclonal Antibodies by FcγRIIIa Affinity Chromatography and Mass Spectrometry. Journal of Medicinal Chemistry, in press (2026). – PubMed – UNIFIND
- Bernardotto S., Frasson I., Faravelli S., Morelli A., Schiavon E., Moscatiello G.Y., Violatto M.B., Pinnola A., Canciani A., Mattarei A., Rossi G., Brini M., Pasetto L., Bonetto V., Bigini P., Forneris F., Richter S.N., Morpurgo M. Efficient SARS-CoV-2 infection antagonization by rhACE2 ectodomain multimerized onto the avidin nucleic-acid-NanoASsembly. Biomaterials, 303, 122394 (2023). – PubMed – UNIFIND
- Brasu N., Elia I., Russo V., Montacchiesi G., Stabile S.A., De Intinis C., Fesi F., Gizzi K., Macagno M., Montone M., Mussolin B., Grifoni A., Faravelli S., Marchese S., Forneris F., De Francesco R., Sette A., Barnaba V., Sottile A., Sapino A., Pace L. Memory CD8+ T cell diversity and B cell responses correlate with protection against SARS-CoV-2 following mRNA vaccination. Nature Immunology, 23, 1445-1456 (2022). – PubMed – UNIFIND
- Bruni M., Cecatiello V., Diaz-Basabe A., Lattanzi G., Mileti E., Monzani S., Pirovano L., Rizzelli F., Visintin C., Bonizzi G., Giani M., Lavitrano M., Faravelli S., Forneris F., Caprioli F., Pelicci P.G., Natoli G., Pasqualato S., Mapelli M., Facciotti F. Persistence of Anti-SARS-CoV-2 Antibodies in Non-Hospitalized COVID-19 Convalescent Health Care Workers. Journal of Clinical Medicine, 9, 3188 (2020). – PubMed – UNIFIND
- Brondino N., Bertoglio F., Forneris F., Faravelli S., Borghesi A., Damiani S., Provenzani U., Nola M., Olivola M., Caviglia M., Politi P., Fusar-Poli L., Fusar-Poli P. A Pilot Study on Covid and Autism: Prevalence, Clinical Presentation and Vaccine Side Effects. Brain Sciences, 11, 860 (2021). – PubMed – UNIFIND
- Varotto-Boccazzi I., Manenti A., Dapporto F., Gourlay L.J., Bisaglia B., Gabrieli P., Forneris F., Faravelli S., Bollati V., Rubolini D., Zuccotti G., Montomoli E., Epis S., Bandi C. Epidemic Preparedness: Leishmania tarentolae as an Easy-to-Handle Tool to Produce Antigens for Viral Diagnosis: Application to COVID-19. Frontiers in Microbiology, 12, 736530 (2021). – PubMed – UNIFIND
- Castelli M., Scietti L., Clementi N., Cavallaro M., Faravelli S., Pinnola A., Crisciuolo E., Diotti R.A., Clementi M., Forneris F., Mancini N. SARS-CoV-2 Spike Affinity and Dynamics Exclude the Strict Requirement of an Intermediate Host. bioRxiv (2021).