Pubblicazioni

Anno

Progetto

Tipologia

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Complement Factor D

Forneris F., Gros P.

Complement Factor D

Pubblicato in:  Handbook of Proteolytic Enzymes, 3, 2841-2848 (2013). - DOI 10.1016/B978-0-12-382219-2.00630-X

Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5.

Peng W.C., de Lau W., Forneris F., Granneman J.C., Huch M., Clevers H., Gros P.

Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5.

Pubblicato in:  Cell Reports, 3, 1885-1892 (2013). - DOI 10.1016/j.celrep.2013.06.009 - PMID 23809763

Proteolysis, Complex Formation and Conformational Changes Drive the Complement Pathways

Gros P., Forneris F.

Proteolysis, Complex Formation and Conformational Changes Drive the Complement Pathways

Pubblicato in:  Advancing Methods for Biomolecular Crystallography, 297-307 (2013). - DOI 10.1007/978-94-007-6232-9_25

The modular serine proteases of the complement cascade.

Forneris F., Wu J., Gros P.

The modular serine proteases of the complement cascade.

Pubblicato in:  Current Opinions in Structural Biology, 22, 333-341 (2012). - DOI 10.1016/j.sbi.2012.04.001 - PMID 22560446

Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.

Hadders M.A., Bubeck D., Roversi P., Hakobyan S., Forneris F., Morgan B.P., Pangburn M.K., Llorca O., Lea S.M., Gros P.

Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.

Pubblicato in:  Cell Reports, 1, 200-207 (2012). - DOI 10.1016/j.celrep.2012.02.003 - PMID 22832194

Structures of C3b in complex with factors B and D give insight into complement convertase formation.

Forneris F., Ricklin D., Wu J., Tzekou A., Wallace R.S., Lambris J.D., Gros P.

Structures of C3b in complex with factors B and D give insight into complement convertase formation.

Pubblicato in:  Science, 330, 1816-1820 (2010). - DOI 10.1126/science.1195821 - PMID 21205667

Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2.

Binda C., Valente S., Romanenghi M., Pilotto S., Cirilli R., Karytinos A., Ciossani G., Botrugno O.A., Forneris F., Tardugno M., Edmondson D.E., Minucci S., Mattevi A., Mai A.

Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2.

Pubblicato in:  Journal of the American Chemical Society, 132, 6827-6833 (2010). - DOI 10.1021/ja101557k - PMID 20415477

Alternative splicing of the histone demethylase LSD1/KDM1 contributes to the modulation of neurite morphogenesis in the mammalian nervous system.

Zibetti C., Adamo A., Binda C., Forneris F., Toffolo E., Verpelli C., Ginelli E., Mattevi A., Sala C., Battaglioli E.

Alternative splicing of the histone demethylase LSD1/KDM1 contributes to the modulation of neurite morphogenesis in the mammalian nervous system.

Pubblicato in:  Journal of Neuroscience, 30, 2521-2532 (2010). - DOI 10.1523/JNEUROSCI.5500-09.2010 - PMID 20164337

Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization.

Villa F., Capasso P., Tortorici M., Forneris F., de Marco A., Mattevi A., Musacchio A.

Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization.

Pubblicato in:  Proceedings of the National Academy of Sciences, U.S.A., 106, 20204-20209 (2009). - DOI 10.1073/pnas.0908485106 - PMID 19918049